The Curing Coma Campaign was launched in 2019 to improve management and outcomes for patients with disorders of consciousness. Since its launch, numerous scientific initiatives have advanced the state-of-the-science in the field of disorders of consciousness and have established a roadmap for how to improve future clinical care for this population. In this session, we will discuss the scientific and clinical contributions of the Curing Coma Campaign, and how they helping to elucidate the neurobiology of impaired consciousness and its recovery.